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Home / Issues / № 2, 2015

Natural flora of Uzbekistan as sources for new medicinal products-botanical nutraceuticals
Belolipov I.V., Abzalova N., Abzalov A.

1. Introduction

In territory of Uzbekistan it grows more than 4500 vascular (high) plant, 1012 genus concerning 167 families. From them about 500 spe­cies are cultural. In Republic more that 1300 Algae, more than 2000 Fungi meet. The bases of flora of the Republic make such large families as Asteraceae-about 600 species, Fabaceae-more than 450 species, Poaceae-more than 250 species, Brassicaceae-more than 200 species, Lamiaceae, Chenopodiaceae, Caryophyllaceae, Liliaceae, Boraginaceae, Rosaceae.

Botanist of Uzbekistan during many years, made numerous expeditions on exploration plants of natural flora both arboreous, and herbaceous, having by food, medicinal, fodder, tannic, aromatic and etc. were carried out. For many species areas of their distribution, the condition of their growth and stocks of vegetative raw material in nature are exploration.

2. Results and Discussion.

Groups of wild-growing plants of natural flora of Uzbekistan on their application in medicine, the food-processing industry and national economy now are established. So there are more than:

-food plants: 350 species of Rosaceae, Alliaceae, Juglandaceae;

-feeding plants: 1700 species of Poaceae, Fabaceae, Chenopodiaceae, Asteraceae familes;

-medicinal plants from Ranunculaceae, Papaveraceae, Asteraceae, Apiaceae-more than 700 species.

Dye plants: Malvaceae, Papaveraceae, Asteraceae families; 200 species of spicy-flavouring, 100 species containing of saponins and more than 400 species of tannin.

In Republics spicy aromatic plants are very much appreciated, the so-called spices used by local population in the life and various branches of national economy are widely used. Berberis, Ziziphora, Origanum, Mediasia, Mentha, Nepeta, Bunium, Cuminum.

Medicinal Plants: Herbal medical tradition is very strong in Uzbekistan. Over 500 species such as Ungernia, Thermopsis, Peganum, Delphinium, Aconitum, Thalictrum, Vinca, Codonopsis, Inula, Tanacetum, are used for the official (industrial) herbal medicine production. In addition, over 200 species including Artemisia, Ziziphora, Achillea, Cichorium, Helichrisum, Hippophae, Polygonum, Hypercum, Rosa, Berberis, Silibum marianum are used in traditional folk medicine.(1)

Medicinal Plants from Central Asia., is very great and important source for the opening new pharmacologicaly components at modern medicine. It is necessary to reveal of new useful properties at plants of natural flora of Uzbekistan, as well as for development and creation of highly effective vegetable medical products, and for creation new dietetic valuable food vegetable additives enriching food stuffs with useful pharmaceutical properties. The last will provide in the sufficient meas­ure and requirement of medical establishments and the population of Republic of Uzbekistan, new pharmaceutical high quality products-botanical nutraceuticals. Long-term researches of botanists have allowed to reveal Uzbekistan, that the greatest in number of species of plants of natural flora Uzbekistan having medicinal and agronomic properties meets in 119 species of Apiaceae family from 57 genus, 88 species of Lamiaceae family from 29 genus, 65 species of Asteraceae family from 26 genus , 46 species of Brassicaceae from 33 genus, 35 species of Rosaceae family from 25 genus, 29 species of Liliaceae family 7 genus, 24 species of Fabaceae from 10 genus. Under the quantitative contents of flavanoides occurs in the families: Polygonaceae, Fabaceae, Euforbiaceae, Apiaceae, Rosaceae are rather perspective: leaves, buds, flowers rather perspective.

Especially the im­portant attentions deserve studying species of family Asteraceae as the perspective plants containing ekdisteroids substances: Serratula sogdianaBge, Rhaponticum integrifolium. Similar substances are found in enough at plants Turkestan Houseleek: Ajuga turkestanica.This plant rather prospective for received many kinds of ekdisteroids substans as turkesteron, ajugosten and others. From the total herbs about 100 species are long since applied in national medi­cine: Artemisia L., Ziziphora L., AchilleaL., Rosa L., Berberis L., Crataegus, Cichorium L., Helichrisum Gaerth., Hippophae L., Polygonum L., Hypericum L., SalviaL., Verbascum L.: more than 500 species are confirmed by pharmaceutical commission and also are transferred to manufacture.

Yet few, a very few, of the Uzbekistan natural flora well known 4500 plant species have been fully pharmacological screened fine chemical analysis and toxicological testing new discovered components for their medicinal effects. But little by little the hidden power plants of Central Asia give us to promiss well for human health deliver prevent from many dangerous disease.

Much remains to be discovered by Uzbekistan Associate Program in Biodiversity inventory collection, training and pharmacological screening and it is therefore of paramount important to maintains the diversity of the Uzbekistan's flora as well as protecting and recording the wealth of knowledge of different culture regarding the use of medicinal plants in Uzbekistan.(2,3,5,6)

However, the potential of natural flora of Uzbekistan is used not full and insufficiently rationally, many wild-growing species till now are not ac­cepted to manufacture of pharmokopie Uzbekistan.

The plants of Lamiaceae family: AjugaTurkestanica; Asteraceae family: Serratula,S.Sogdiana, species of Rhaponticum genus: Rh. Integrifolium, Rh. Carthamoides and others.

With increase of growth of the population of Uzbekistan the increasing of manufacture of the foodstuffs having not only by caloric content, but also the useful dietary, pharmaceutical properties enriched natural nutraceuticals, protecting the organism of the person from adverse condi­tions of the environment is required also.

Nowadays the world markets of the pharmaceutical goods in total amount 300 billion US dollars on 25 % consists of the substances re­ceived from plants and thus the market botanical nutraceuticals makes 5 billion US dollars. Only not the most part of species of the high plants from 250 thousand species is well enough investigated in the pharma­ceutical relation.(4)) Thus, the natural flora of Uzbekistan represents the big interest for many well developed countries, including USA, Germany, Japan, France and others as a source for reception of new, qualitative components for manufacture of new pharmaceutical products.

The further development of the given problem in Uzbekistan restrains the insufficient (eve) of financing and the out-of-date material resources of researches.

Conclusion: Only combined efforts scientific of Uzbekistan, USA, Germany, Japan, China, France and others can be reached development of deeper studying of botanical re­sources of natural flora of Uzbekistan for revealing new perspective species of plants with the purpose of their application in quality botani­cal nutraceuticals. The potential for discovery of additional medicines from wild plants of Uzbekistan's flora is tremendous.

Our opinion we began deeply study so many of plants of natural flora of Uzbekistan by new methods fine chemical analysis for screening plants, containing biologically active substances for future manufacture of new pharmaceutical products - botanical nutraceuticals or functional foods in Uzbekistan. Of course, we receive undoubted success and our cooperation only strengthen. The major strengths of our project included co­operation of an excellent team of scientists from Germany, Japan, Koreja, China, USA and Uzbekistan. Uzbekistan is actively promoting cooperation with forein states and international non-governmental organizatiоn in sphere of ecology and nature conservation. The potential for discovery of additional medicines from willd plants of Uzbekistans flora is tremendous.

The hidden power of plants of natural flora of Uzbekistan must be discovered and used up for humanity all over the World.



References:
1. Medicinal Plants of Central Asia:Uzbekistan and Kyrgyzstan. Eisenman Sasha, David E. Zaurov and LenaStruwe. 2013.Springer, 233 Springer street New York, NY 10013; 340 p.

2. Challenges and Tribulation in the Commersalization of New Crops:Aromatic and Medicinal Plants. James E. Simon, Elton Jefthas, Erica Renaud, IlyaRaskin, PierreTannous and others. Korean J. Medicinal Crop Sci.10(4):303-313 pp, 2002.

3. Sarah Jane Gurr, Josephine Peach. The hidden power of plants. Garden, vol. 121, parts 5, may, 1996, 262-264 pp.

4. Plants and human health in the twenty-first century. IlyaRaskin,David M. Ribnicky, SlavkoKomarnytsky, NeboisaIlic and other. Thends in Biotechnology. Vol. 20. No 12. December. 2002. 522-526 pp.

5. I.V.Belolipov, Moul Day, IlyaRaskin others. Plant Extracts from Central Asia showing AntiflammatoriActivites in GeneExpressian Assays. J. PhytotherapyReserch. Phytoher. Res. (2008). Pablieshed online in Wiley interscience (www. intercince) Wiley Com.

6. Moul Day,I.Belolipov, Salohidin Zakirov, Anarbek Akimaliev, Ilya Raskin, Ishinbay Sodombekov.Anti-inflammatory Botanicals- Phytochemicals,Aging and Healh..CRC. Taylor @ Francis group. Boca Raton London New York,2008,77-89 pp.



Bibliographic reference

Belolipov I.V., Abzalova N., Abzalov A. Natural flora of Uzbekistan as sources for new medicinal products-botanical nutraceuticals. International Journal Of Applied And Fundamental Research. – 2015. – № 2 –
URL: www.science-sd.com/461-24823 (24.04.2024).